Sugar-Sweetened Beverage and Vascular Function

Sugar-sweetened beverages (SSBs) are some of the most commonly consumed beverages around the world. Sweeteners used in these beverages include sucrose, fruit juices, and high fructose corn syrup. Increased consumption of these beverages has been causally linked to obesity, diabetes mellitus/metabolic syndrome, hypertension, gout, and cardiovascular disease. On the basis of a comparative risk analysis model, Micha et al concluded that, in 2012 in the United States, ≈45% of 702 308 deaths attributed to heart disease, stroke, and type 2 diabetes mellitus were associated with consumption of 10 dietary factors, with consumption of SSB accounting for 7.4% of cardiometabolic deaths. The consumption of SSB accounted for 10.8% of deaths from coronary heart disease and 14.8% of type 2 diabetes mellitus–related deaths.